ChAdOx1-vectored Lassa fever vaccine elicits a robust cellular and humoral immune response and protects guinea pigs against lethal Lassa virus challenge

Lassa virus (LASV) infects hundreds of thousands of individuals each year, highlighting the need for the accelerated development of preventive, diagnostic, and therapeutic interventions. To date, no vaccine has been licensed for LASV. ChAdOx1-Lassa-GPC is a chimpanzee adenovirus-vectored vaccine enc...

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Detalhes bibliográficos
Publicado no:NPJ Vaccines
Main Authors: Fischer, Robert J., Purushotham, Jyothi N., van Doremalen, Neeltje, Sebastian, Sarah, Meade-White, Kimberly, Cordova, Kathleen, Letko, Michael, Jeremiah Matson, M., Feldmann, Friederike, Haddock, Elaine, LaCasse, Rachel, Saturday, Greg, Lambe, Teresa, Gilbert, Sarah C., Munster, Vincent J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925663/
https://ncbi.nlm.nih.gov/pubmed/33654106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-021-00291-x
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