A single-dose ChAdOx1-vectored vaccine provides complete protection against Nipah Bangladesh and Malaysia in Syrian golden hamsters

Nipah virus (NiV) is a highly pathogenic re-emerging virus that causes outbreaks in South East Asia. Currently, no approved and licensed vaccine or antivirals exist. Here, we investigated the efficacy of ChAdOx1 NiV(B), a simian adenovirus-based vaccine encoding NiV glycoprotein (G) Bangladesh, in S...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: van Doremalen, Neeltje, Lambe, Teresa, Sebastian, Sarah, Bushmaker, Trenton, Fischer, Robert, Feldmann, Friederike, Haddock, Elaine, Letko, Michael, Avanzato, Victoria A., Rissanen, Ilona, LaCasse, Rachel, Scott, Dana, Bowden, Thomas A., Gilbert, Sarah, Munster, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581282/
https://ncbi.nlm.nih.gov/pubmed/31170144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007462
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