A single-dose ChAdOx1-vectored vaccine provides complete protection against Nipah Bangladesh and Malaysia in Syrian golden hamsters

Nipah virus (NiV) is a highly pathogenic re-emerging virus that causes outbreaks in South East Asia. Currently, no approved and licensed vaccine or antivirals exist. Here, we investigated the efficacy of ChAdOx1 NiV(B), a simian adenovirus-based vaccine encoding NiV glycoprotein (G) Bangladesh, in S...

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Publicat a:PLoS Negl Trop Dis
Autors principals: van Doremalen, Neeltje, Lambe, Teresa, Sebastian, Sarah, Bushmaker, Trenton, Fischer, Robert, Feldmann, Friederike, Haddock, Elaine, Letko, Michael, Avanzato, Victoria A., Rissanen, Ilona, LaCasse, Rachel, Scott, Dana, Bowden, Thomas A., Gilbert, Sarah, Munster, Vincent
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581282/
https://ncbi.nlm.nih.gov/pubmed/31170144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007462
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