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Antivirals that target the host IMPα/β1-virus interface
Although transport into the nucleus mediated by the importin (IMP) α/β1-heterodimer is central to viral infection, small molecule inhibitors of IMPα/β1-dependent nuclear import have only been described and shown to have antiviral activity in the last decade. Their robust antiviral activity is due to...
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| Published in: | Biochem Soc Trans |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Portland Press Ltd.
2021
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7925013/ https://ncbi.nlm.nih.gov/pubmed/33439253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20200568 |
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