Novel Flavivirus Antiviral That Targets the Host Nuclear Transport Importin α/β1 Heterodimer

Dengue virus (DENV) threatens almost 70% of the world’s population, with no effective vaccine or therapeutic currently available. A key contributor to infection is nuclear localisation in the infected cell of DENV nonstructural protein 5 (NS5) through the action of the host importin (IMP) α/β1 prote...

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Publicado no:Cells
Main Authors: Yang, Sundy N. Y., Atkinson, Sarah C., Fraser, Johanna E., Wang, Chunxiao, Maher, Belinda, Roman, Noelia, Forwood, Jade K., Wagstaff, Kylie M., Borg, Natalie A., Jans, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468590/
https://ncbi.nlm.nih.gov/pubmed/30909636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8030281
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