Structure of human endo-α-1,2-mannosidase (MANEA), an antiviral host-glycosylation target

Mammalian protein N-linked glycosylation is critical for glycoprotein folding, quality control, trafficking, recognition, and function. N-linked glycans are synthesized from Glc(3)Man(9)GlcNAc(2) precursors that are trimmed and modified in the endoplasmic reticulum (ER) and Golgi apparatus by glycos...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sobala, Łukasz F., Fernandes, Pearl Z., Hakki, Zalihe, Thompson, Andrew J., Howe, Jonathon D., Hill, Michelle, Zitzmann, Nicole, Davies, Scott, Stamataki, Zania, Butters, Terry D., Alonzi, Dominic S., Williams, Spencer J., Davies, Gideon J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703563/
https://ncbi.nlm.nih.gov/pubmed/33154157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013620117
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