Structure of human endo-α-1,2-mannosidase (MANEA), an antiviral host-glycosylation target

Mammalian protein N-linked glycosylation is critical for glycoprotein folding, quality control, trafficking, recognition, and function. N-linked glycans are synthesized from Glc(3)Man(9)GlcNAc(2) precursors that are trimmed and modified in the endoplasmic reticulum (ER) and Golgi apparatus by glycos...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Sobala, Łukasz F., Fernandes, Pearl Z., Hakki, Zalihe, Thompson, Andrew J., Howe, Jonathon D., Hill, Michelle, Zitzmann, Nicole, Davies, Scott, Stamataki, Zania, Butters, Terry D., Alonzi, Dominic S., Williams, Spencer J., Davies, Gideon J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2020
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703563/
https://ncbi.nlm.nih.gov/pubmed/33154157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013620117
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