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HIV-1 integrase is capable of targeting DNA to the nucleus via an Importin α/β-dependent mechanism

In addition to its well-documented role in integration of the viral genome, the HIV-1 enzyme IN (integrase) is thought to be involved in the preceding step of importing the viral cDNA into the nucleus. The ability of HIV to transport its cDNA through an intact nuclear envelope allows HIV-1 to infect...

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Bibliografiska uppgifter
Huvudupphovsmän: Hearps, Anna C., Jans, David A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Portland Press Ltd. 2006
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1559465/
https://ncbi.nlm.nih.gov/pubmed/16716146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060466
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