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Importin α3 Interacts with HIV-1 Integrase and Contributes to HIV-1 Nuclear Import and Replication

HIV-1 employs the cellular nuclear import machinery to actively transport its preintegration complex (PIC) into the nucleus for integration of the viral DNA. Several viral karyophilic proteins and cellular import factors have been suggested to contribute to HIV-1 PIC nuclear import and replication....

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Detalhes bibliográficos
Main Authors: Ao, Zhujun, Danappa Jayappa, Kallesh, Wang, Binchen, Zheng, Yingfeng, Kung, Sam, Rassart, Eric, Depping, Reinhard, Kohler, Matthias, Cohen, Eric A., Yao, Xiaojian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919037/
https://ncbi.nlm.nih.gov/pubmed/20554775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00508-10
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