Učitavanje...
Double inhibition and activation mechanisms of Ephexin family RhoGEFs
Ephexin family guanine nucleotide exchange factors (GEFs) transfer signals from Eph tyrosine kinase receptors to Rho GTPases, which play critical roles in diverse cellular processes, as well as cancers and brain disorders. Here, we elucidate the molecular basis underlying inhibition and activation o...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2021
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7923574/ https://ncbi.nlm.nih.gov/pubmed/33597305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2024465118 |
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