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Comparison of SYK Signaling Networks Reveals the Potential Molecular Determinants of Its Tumor-Promoting and Suppressing Functions

Spleen tyrosine kinase (SYK) can behave as an oncogene or a tumor suppressor, depending on the cell and tissue type. As pharmacological SYK inhibitors are currently evaluated in clinical trials, it is important to gain more information on the molecular mechanisms underpinning these opposite roles. T...

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Publicat a:Biomolecules
Autors principals: Buffard, Marion, Naldi, Aurélien, Freiss, Gilles, Deckert, Marcel, Radulescu, Ovidiu, Coopman, Peter J., Larive, Romain M.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923165/
https://ncbi.nlm.nih.gov/pubmed/33670716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11020308
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