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Comparison of SYK Signaling Networks Reveals the Potential Molecular Determinants of Its Tumor-Promoting and Suppressing Functions

Spleen tyrosine kinase (SYK) can behave as an oncogene or a tumor suppressor, depending on the cell and tissue type. As pharmacological SYK inhibitors are currently evaluated in clinical trials, it is important to gain more information on the molecular mechanisms underpinning these opposite roles. T...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Buffard, Marion, Naldi, Aurélien, Freiss, Gilles, Deckert, Marcel, Radulescu, Ovidiu, Coopman, Peter J., Larive, Romain M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923165/
https://ncbi.nlm.nih.gov/pubmed/33670716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11020308
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