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Comparison of SYK Signaling Networks Reveals the Potential Molecular Determinants of Its Tumor-Promoting and Suppressing Functions

Spleen tyrosine kinase (SYK) can behave as an oncogene or a tumor suppressor, depending on the cell and tissue type. As pharmacological SYK inhibitors are currently evaluated in clinical trials, it is important to gain more information on the molecular mechanisms underpinning these opposite roles. T...

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Bibliografske podrobnosti
izdano v:Biomolecules
Main Authors: Buffard, Marion, Naldi, Aurélien, Freiss, Gilles, Deckert, Marcel, Radulescu, Ovidiu, Coopman, Peter J., Larive, Romain M.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923165/
https://ncbi.nlm.nih.gov/pubmed/33670716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11020308
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