Challenges and Opportunities for Drug Repositioning in Fibrodysplasia Ossificans Progressiva

Fibrodysplasia ossificans progressiva (FOP) is an ultrarare congenital disease that progresses through intermittent episodes of bone formation at ectopic sites. FOP patients carry heterozygous gene point mutations in activin A receptor type I ACVR1, encoding the bone morphogenetic protein (BMP) type...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Biomedicines
Päätekijät: Ventura, Francesc, Williams, Eleanor, Ikeya, Makoto, Bullock, Alex N., ten Dijke, Peter, Goumans, Marie-José, Sanchez-Duffhues, Gonzalo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2021
Aiheet:
Review
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7922784/
https://ncbi.nlm.nih.gov/pubmed/33669809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9020213
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