Chemogenetic ON and OFF switches for RNA virus replication

Therapeutic application of RNA viruses as oncolytic agents or gene vectors requires a tight control of virus activity if toxicity is a concern. Here we present a regulator switch for RNA viruses using a conditional protease approach, in which the function of at least one viral protein essential for...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Heilmann, E., Kimpel, J., Hofer, B., Rössler, A., Blaas, I., Egerer, L., Nolden, T., Urbiola, C., Kräusslich, H. G., Wollmann, G., von Laer, D.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7921684/
https://ncbi.nlm.nih.gov/pubmed/33649317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21630-5
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires