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PKA-RIIβ autophosphorylation modulates PKA activity and seizure phenotypes in mice

Temporal lobe epilepsy (TLE) is one of the most common and intractable neurological disorders in adults. Dysfunctional PKA signaling is causally linked to the TLE. However, the mechanism underlying PKA involves in epileptogenesis is still poorly understood. In the present study, we found the autopho...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Commun Biol
Hauptverfasser: Zhang, Jingliang, Zhang, Chenyu, Chen, Xiaoling, Wang, Bingwei, Ma, Weining, Yang, Yang, Zheng, Ruimao, Huang, Zhuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7921646/
https://ncbi.nlm.nih.gov/pubmed/33649504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01748-4
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