Puerarin ameliorated pressure overload-induced cardiac hypertrophy in ovariectomized rats through activation of the PPARα/PGC-1 pathway

Estrogen deficiency induces cardiac dysfunction and increases the risk of cardiovascular disease in postmenopausal women and in those who underwent bilateral oophorectomy. Previous evidence suggests that puerarin, a phytoestrogen, exerts beneficial effects on cardiac function in patients with cardia...

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Dettagli Bibliografici
Pubblicato in:Acta Pharmacol Sin
Autori principali: Hou, Ning, Huang, Yin, Cai, Shao-ai, Yuan, Wen-chang, Li, Li-rong, Liu, Xia-wen, Zhao, Gan-jian, Qiu, Xiao-xia, Li, Ai-qun, Cheng, Chuan-fang, Liu, Shi-ming, Chen, Xiao-hui, Cai, Dao-feng, Xie, Jing-xuan, Chen, Min-sheng, Luo, Cheng-feng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Singapore 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7921143/
https://ncbi.nlm.nih.gov/pubmed/32504066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-020-0401-y
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