MiR-30c/PGC-1β protects against diabetic cardiomyopathy via PPARα

BACKGROUND: Metabolic abnormalities have been implicated as a causal event in diabetic cardiomyopathy (DCM). However, the mechanisms underlying cardiac metabolic disorder in DCM were not fully understood. RESULTS: Db/db mice, palmitate treated H9c2 cells and primary neonatal rat cardiomyocytes were...

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Dades bibliogràfiques
Publicat a:Cardiovasc Diabetol
Autors principals: Yin, Zhongwei, Zhao, Yanru, He, Mengying, Li, Huaping, Fan, Jiahui, Nie, Xiang, Yan, Mengwen, Chen, Chen, Wang, Dao Wen
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Original Investigation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329097/
https://ncbi.nlm.nih.gov/pubmed/30635067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-019-0811-7
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