Nrf2 Is a Key Regulator on Puerarin Preventing Cardiac Fibrosis and Upregulating Metabolic Enzymes UGT1A1 in Rats

Puerarin is an isoflavone isolated from Radix puerariae. Emerging evidence shown that puerarin possesses therapeutic benefits that aid in the prevention of cardiovascular diseases. In this study, we evaluated the effects of puerarin on oxidative stress and cardiac fibrosis induced by abdominal aorti...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Cai, Shao-Ai, Hou, Ning, Zhao, Gan-Jian, Liu, Xia-Wen, He, Ying-Yan, Liu, Hai-Lin, Hua, Yong-Quan, Li, Li-Rong, Huang, Yin, Ou, Cai-Wen, Luo, Cheng-Feng, Chen, Min-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997811/
https://ncbi.nlm.nih.gov/pubmed/29928229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00540
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