Metformin Ameliorates Gestational Diabetes Mellitus-Induced Endothelial Dysfunction via Downregulation of p65 and Upregulation of Nrf2

Gestational diabetes mellitus (GDM) causes oxidative stress in mothers and infants and causes vascular endothelial dysfunction, which is a key factor for maternal and fetal cardiovascular diseases in the later stage of GDM, seriously threatening the life and health of mothers and infants. Nowadays,...

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Vydáno v:Front Pharmacol
Hlavní autoři: Sun, Cong Cong, Lai, Ya Nan, Wang, Wen Huan, Xu, Xiao Min, Li, Xiao Qing, Wang, Hai, Zheng, Jia Yong, Zheng, Jian Qiong
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581851/
https://ncbi.nlm.nih.gov/pubmed/33162888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.575390
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