Impairment of Proteasome Function in Podocytes Leads to CKD

BACKGROUND: The ubiquitin-proteasome system (UPS) and the autophagy-lysosomal system (APLS) are major intracellular degradation procedures. The importance of the APLS in podocytes is established, but the role of the UPS is not well understood. METHODS: To investigate the role of the UPS in podocytes...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Makino, Shin-ichi, Shirata, Naritoshi, Oliva Trejo, Juan Alejandro, Yamamoto-Nonaka, Kanae, Yamada, Hiroyuki, Miyake, Takafumi, Mori, Kiyoshi, Nakagawa, Takahiko, Tashiro, Yoshitaka, Yamashita, Hirofumi, Yanagita, Motoko, Takahashi, Ryosuke, Asanuma, Katsuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2021
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920174/
https://ncbi.nlm.nih.gov/pubmed/33510039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019101025
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