Glomerulosclerosis Induced by Deficiency of Membrane-Associated Guanylate Kinase Inverted 2 in Kidney Podocytes

Membrane-associated guanylate kinase inverted 2 (MAGI-2) is a component of the slit diaphragm (SD) of glomerular podocytes. Here, we investigated the podocyte-specific function of MAGI-2 using newly generated podocyte-specific MAGI-2–knockout (MAGI-2–KO) mice. Compared with podocytes from wild-type...

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Bibliografiske detaljer
Udgivet i:J Am Soc Nephrol
Main Authors: Shirata, Naritoshi, Ihara, Kan-ichiro, Yamamoto-Nonaka, Kanae, Seki, Takuto, Makino, Shin-ichi, Oliva Trejo, Juan Alejandro, Miyake, Takafumi, Yamada, Hiroyuki, Campbell, Kirk Nicholas, Nakagawa, Takahiko, Mori, Kiyoshi, Yanagita, Motoko, Mundel, Peter, Nishimori, Katsuhiko, Asanuma, Katsuhiko
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2017
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576941/
https://ncbi.nlm.nih.gov/pubmed/28539383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016121356
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