Cathepsin D in Podocytes Is Important in the Pathogenesis of Proteinuria and CKD

Studies have revealed many analogies between podocytes and neurons, and these analogies may be key to elucidating the pathogenesis of podocyte injury. Cathepsin D (CD) is a representative aspartic proteinase in lysosomes. Central nervous system neurons in CD-deficient mice exhibit a form of lysosoma...

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Dades bibliogràfiques
Publicat a:J Am Soc Nephrol
Autors principals: Yamamoto-Nonaka, Kanae, Koike, Masato, Asanuma, Katsuhiko, Takagi, Miyuki, Oliva Trejo, Juan Alejandro, Seki, Takuto, Hidaka, Teruo, Ichimura, Koichiro, Sakai, Tatsuo, Tada, Norihiro, Ueno, Takashi, Uchiyama, Yasuo, Tomino, Yasuhiko
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2016
Matèries:
Basic Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004641/
https://ncbi.nlm.nih.gov/pubmed/26823550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015040366
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