Cathepsin D in Podocytes Is Important in the Pathogenesis of Proteinuria and CKD

Studies have revealed many analogies between podocytes and neurons, and these analogies may be key to elucidating the pathogenesis of podocyte injury. Cathepsin D (CD) is a representative aspartic proteinase in lysosomes. Central nervous system neurons in CD-deficient mice exhibit a form of lysosoma...

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Bibliografske podrobnosti
izdano v:J Am Soc Nephrol
Main Authors: Yamamoto-Nonaka, Kanae, Koike, Masato, Asanuma, Katsuhiko, Takagi, Miyuki, Oliva Trejo, Juan Alejandro, Seki, Takuto, Hidaka, Teruo, Ichimura, Koichiro, Sakai, Tatsuo, Tada, Norihiro, Ueno, Takashi, Uchiyama, Yasuo, Tomino, Yasuhiko
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2016
Teme:
Basic Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004641/
https://ncbi.nlm.nih.gov/pubmed/26823550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015040366
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