Cathepsin D in Podocytes Is Important in the Pathogenesis of Proteinuria and CKD

Studies have revealed many analogies between podocytes and neurons, and these analogies may be key to elucidating the pathogenesis of podocyte injury. Cathepsin D (CD) is a representative aspartic proteinase in lysosomes. Central nervous system neurons in CD-deficient mice exhibit a form of lysosoma...

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Detalles Bibliográficos
Publicado en:J Am Soc Nephrol
Main Authors: Yamamoto-Nonaka, Kanae, Koike, Masato, Asanuma, Katsuhiko, Takagi, Miyuki, Oliva Trejo, Juan Alejandro, Seki, Takuto, Hidaka, Teruo, Ichimura, Koichiro, Sakai, Tatsuo, Tada, Norihiro, Ueno, Takashi, Uchiyama, Yasuo, Tomino, Yasuhiko
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Nephrology 2016
Assuntos:
Basic Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004641/
https://ncbi.nlm.nih.gov/pubmed/26823550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015040366
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