Cathepsin D in Podocytes Is Important in the Pathogenesis of Proteinuria and CKD

Studies have revealed many analogies between podocytes and neurons, and these analogies may be key to elucidating the pathogenesis of podocyte injury. Cathepsin D (CD) is a representative aspartic proteinase in lysosomes. Central nervous system neurons in CD-deficient mice exhibit a form of lysosoma...

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Bibliografiske detaljer
Udgivet i:J Am Soc Nephrol
Main Authors: Yamamoto-Nonaka, Kanae, Koike, Masato, Asanuma, Katsuhiko, Takagi, Miyuki, Oliva Trejo, Juan Alejandro, Seki, Takuto, Hidaka, Teruo, Ichimura, Koichiro, Sakai, Tatsuo, Tada, Norihiro, Ueno, Takashi, Uchiyama, Yasuo, Tomino, Yasuhiko
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2016
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004641/
https://ncbi.nlm.nih.gov/pubmed/26823550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015040366
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