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Overview of the Assays to Probe O-Linked β-N-Acetylglucosamine Transferase Binding and Activity

O-GlcNAcylation is a posttranslational modification that occurs at serine and threonine residues of protein substrates by the addition of O-linked β-d-N-acetylglucosamine (GlcNAc) moiety. Two enzymes are involved in this modification: O-GlcNac transferase (OGT), which attaches the GlcNAc residue to...

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Balsollier, Cyril, Pieters, Roland J., Anderluh, Marko
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920051/
https://ncbi.nlm.nih.gov/pubmed/33669256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26041037
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