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Overview of the Assays to Probe O-Linked β-N-Acetylglucosamine Transferase Binding and Activity

O-GlcNAcylation is a posttranslational modification that occurs at serine and threonine residues of protein substrates by the addition of O-linked β-d-N-acetylglucosamine (GlcNAc) moiety. Two enzymes are involved in this modification: O-GlcNac transferase (OGT), which attaches the GlcNAc residue to...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Balsollier, Cyril, Pieters, Roland J., Anderluh, Marko
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920051/
https://ncbi.nlm.nih.gov/pubmed/33669256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26041037
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