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Polyamine Analog Diethylnorspermidine Restricts Coxsackievirus B3 and Is Overcome by 2A Protease Mutation In Vitro

Enteroviruses, including Coxsackievirus B3 (CVB3), are pervasive pathogens that cause significant disease, including cardiomyopathies. Unfortunately, no treatments or vaccines are available for infected individuals. We identified the host polyamine pathway as a potential drug target, as inhibiting p...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Hulsebosch, Bridget M., Mounce, Bryan C.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920041/
https://ncbi.nlm.nih.gov/pubmed/33669273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13020310
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