YAP plays a crucial role in the development of cardiomyopathy in lysosomal storage diseases

Lysosomal dysfunction caused by mutations in lysosomal genes results in lysosomal storage disorder (LSD), characterized by accumulation of damaged proteins and organelles in cells and functional abnormalities in major organs, including the heart, skeletal muscle, and liver. In LSD, autophagy is inhi...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Ikeda, Shohei, Nah, Jihoon, Shirakabe, Akihiro, Zhai, Peiyong, Oka, Shin-ichi, Sciarretta, Sebastiano, Guan, Kun-Liang, Shimokawa, Hiroaki, Sadoshima, Junichi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2021
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919732/
https://ncbi.nlm.nih.gov/pubmed/33373332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI143173
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