Small-Angle X-ray Scattering Models of APOBEC3B Catalytic Domain in a Complex with a Single-Stranded DNA Inhibitor

In normal cells APOBEC3 (A3A-A3H) enzymes as part of the innate immune system deaminate cytosine to uracil on single-stranded DNA (ssDNA) to scramble DNA in order to give protection against a range of exogenous retroviruses, DNA-based parasites, and endogenous retroelements. However, some viruses an...

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Publicado en:Viruses
Main Authors: Barzak, Fareeda M., Ryan, Timothy M., Kvach, Maksim V., Kurup, Harikrishnan M., Aihara, Hideki, Harris, Reuben S., Filichev, Vyacheslav V., Harjes, Elena, Jameson, Geoffrey B.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7918907/
https://ncbi.nlm.nih.gov/pubmed/33673243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13020290
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