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Copper‐Catalyzed Addition of Grignard Reagents to in situ Generated Indole‐Derived Vinylogous Imines

Chiral indole derivatives are ubiquitous motifs in pharmaceuticals and alkaloids. Herein, the first protocol for catalytic asymmetric conjugate addition of Grignard reagents to various sulfonyl indoles, offering a straightforward approach for the synthesis of chiral 3‐sec‐alkyl‐substituted indoles i...

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Detaylı Bibliyografya
Yayımlandı:Chemistry
Asıl Yazarlar: Ge, Luo, Zurro, Mercedes, Harutyunyan, Syuzanna R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7918645/
https://ncbi.nlm.nih.gov/pubmed/32960461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202004232
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