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Strategies to Target ADAM17 in Disease: From Its Discovery to the iRhom Revolution

For decades, disintegrin and metalloproteinase 17 (ADAM17) has been the object of deep investigation. Since its discovery as the tumor necrosis factor convertase, it has been considered a major drug target, especially in the context of inflammatory diseases and cancer. Nevertheless, the development...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Molecules
Päätekijät: Calligaris, Matteo, Cuffaro, Doretta, Bonelli, Simone, Spanò, Donatella Pia, Rossello, Armando, Nuti, Elisa, Scilabra, Simone Dario
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7916773/
https://ncbi.nlm.nih.gov/pubmed/33579029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26040944
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