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Strategies to Target ADAM17 in Disease: From Its Discovery to the iRhom Revolution
For decades, disintegrin and metalloproteinase 17 (ADAM17) has been the object of deep investigation. Since its discovery as the tumor necrosis factor convertase, it has been considered a major drug target, especially in the context of inflammatory diseases and cancer. Nevertheless, the development...
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| Publicado en: | Molecules |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7916773/ https://ncbi.nlm.nih.gov/pubmed/33579029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26040944 |
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