Differential Induction of the ADAM17 Regulators iRhom1 and 2 in Endothelial Cells

Background: Endothelial function significantly depends on the proteolytic release of surface expressed signal molecules, their receptors and adhesion molecules via the metalloproteinase ADAM17. The pseudoproteases iRhom1 and 2 independently function as adapter proteins for ADAM17 and are essential f...

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Bibliographic Details
Published in:Front Cardiovasc Med
Main Authors: Babendreyer, Aaron, Rojas-González, Diana M., Giese, Anja Adelina, Fellendorf, Sandra, Düsterhöft, Stefan, Mela, Petra, Ludwig, Andreas
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Cardiovascular Medicine
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736406/
https://ncbi.nlm.nih.gov/pubmed/33335915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2020.610344
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