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The Role of mTOR Signaling as a Therapeutic Target in Cancer

The aim of this review was to summarize current available information about the role of phosphatidylinositol-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling in cancer as a potential target for new therapy options. The mTOR and PI3K/AKT/mTORC1 (mTOR complex 1) signaling are critica...

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Pubblicato in:Int J Mol Sci
Autori principali: Popova, Nadezhda V., Jücker, Manfred
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7916160/
https://ncbi.nlm.nih.gov/pubmed/33572326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041743
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