Dysregulation of PGC-1α-Dependent Transcriptional Programs in Neurological and Developmental Disorders: Therapeutic Challenges and Opportunities

Substantial evidence indicates that mitochondrial impairment contributes to neuronal dysfunction and vulnerability in disease states, leading investigators to propose that the enhancement of mitochondrial function should be considered a strategy for neuroprotection. However, multiple attempts to imp...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cells
Auteurs principaux: McMeekin, Laura J., Fox, Stephanie N., Boas, Stephanie M., Cowell, Rita M.
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Review
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915819/
https://ncbi.nlm.nih.gov/pubmed/33572179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020352
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