Dysregulation of PGC-1α-Dependent Transcriptional Programs in Neurological and Developmental Disorders: Therapeutic Challenges and Opportunities

Substantial evidence indicates that mitochondrial impairment contributes to neuronal dysfunction and vulnerability in disease states, leading investigators to propose that the enhancement of mitochondrial function should be considered a strategy for neuroprotection. However, multiple attempts to imp...

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Publicado en:Cells
Main Authors: McMeekin, Laura J., Fox, Stephanie N., Boas, Stephanie M., Cowell, Rita M.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
Assuntos:
Review
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915819/
https://ncbi.nlm.nih.gov/pubmed/33572179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020352
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