Phosphoproteomic Landscape of AML Cells Treated with the ATP-Competitive CK2 Inhibitor CX-4945

Casein kinase 2 (CK2) regulates a plethora of proteins with pivotal roles in solid and hematological neoplasia. Particularly, in acute myeloid leukemia (AML) CK2 has been pointed as an attractive therapeutic target and prognostic marker. Here, we explored the impact of CK2 inhibition over the phosph...

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Vydáno v:Cells
Hlavní autoři: Rosales, Mauro, Rodríguez-Ulloa, Arielis, Besada, Vladimir, Ramón, Ailyn C., Pérez, George V., Ramos, Yassel, Guirola, Osmany, González, Luis J., Zettl, Katharina, Wiśniewski, Jacek R., Perera, Yasser, Perea, Silvio E.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915770/
https://ncbi.nlm.nih.gov/pubmed/33562780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020338
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