Effects of the CK2 Inhibitors CX-4945 and CX-5011 on Drug-Resistant Cells

CK2 is a pleiotropic protein kinase, which regulates many survival pathways and plays a global anti-apoptotic function. It is highly expressed in tumor cells, and is presently considered a promising therapeutic target. Among the many inhibitors available for this kinase, the recently developed CX-49...

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Bibliographische Detailangaben
Hauptverfasser: Zanin, Sofia, Borgo, Christian, Girardi, Cristina, O'Brien, Sean E., Miyata, Yoshihiko, Pinna, Lorenzo A., Donella-Deana, Arianna, Ruzzene, Maria
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493520/
https://ncbi.nlm.nih.gov/pubmed/23145120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049193
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