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Different Persistence of the Cellular Effects Promoted by Protein Kinase CK2 Inhibitors CX-4945 and TDB

We compare the cellular efficacy of two selective and cell permeable inhibitors of the antiapoptotic kinase CK2. One inhibitor, CX-4945, is already in clinical trials as antitumor drug, while the other, TDB, has been recently successfully employed to demonstrate the implication of CK2 in cellular (d...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Girardi, Cristina, Ottaviani, Daniele, Pinna, Lorenzo A., Ruzzene, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628960/
https://ncbi.nlm.nih.gov/pubmed/26558259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/185736
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