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Targeting Protein Kinase CK2: Evaluating CX-4945 Potential for GL261 Glioblastoma Therapy in Immunocompetent Mice

Glioblastoma (GBM) causes poor survival in patients even with aggressive treatment. Temozolomide (TMZ) is the standard chemotherapeutic choice for GBM treatment but resistance always ensues. Protein kinase CK2 (CK2) contributes to tumour development and proliferation in cancer, and it is overexpress...

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Bibliografiske detaljer
Udgivet i:Pharmaceuticals (Basel)
Main Authors: Ferrer-Font, Laura, Villamañan, Lucia, Arias-Ramos, Nuria, Vilardell, Jordi, Plana, Maria, Ruzzene, Maria, Pinna, Lorenzo A., Itarte, Emilio, Arús, Carles, Candiota, Ana Paula
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374428/
https://ncbi.nlm.nih.gov/pubmed/28208677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph10010024
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