Phosphoproteomic Landscape of AML Cells Treated with the ATP-Competitive CK2 Inhibitor CX-4945

Casein kinase 2 (CK2) regulates a plethora of proteins with pivotal roles in solid and hematological neoplasia. Particularly, in acute myeloid leukemia (AML) CK2 has been pointed as an attractive therapeutic target and prognostic marker. Here, we explored the impact of CK2 inhibition over the phosph...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Rosales, Mauro, Rodríguez-Ulloa, Arielis, Besada, Vladimir, Ramón, Ailyn C., Pérez, George V., Ramos, Yassel, Guirola, Osmany, González, Luis J., Zettl, Katharina, Wiśniewski, Jacek R., Perera, Yasser, Perea, Silvio E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915770/
https://ncbi.nlm.nih.gov/pubmed/33562780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020338
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