Targeting of Protein Kinase CK2 in Acute Myeloid Leukemia Cells Using the Clinical-Grade Synthetic-Peptide CIGB-300

Protein kinase CK2 has emerged as an attractive therapeutic target in acute myeloid leukemia (AML), an advent that becomes particularly relevant since the treatment of this hematological neoplasia remains challenging. Here we explored for the first time the effect of the clinical-grade peptide-based...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Rosales, Mauro, Pérez, George V., Ramón, Ailyn C., Cruz, Yiliam, Rodríguez-Ulloa, Arielis, Besada, Vladimir, Ramos, Yassel, Vázquez-Blomquist, Dania, Caballero, Evelin, Aguilar, Daylen, González, Luis J., Zettl, Katharina, Wiśniewski, Jacek R., Yang, Ke, Perera, Yasser, Perea, Silvio E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301452/
https://ncbi.nlm.nih.gov/pubmed/34356831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9070766
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