Targeting of Protein Kinase CK2 in Acute Myeloid Leukemia Cells Using the Clinical-Grade Synthetic-Peptide CIGB-300

Protein kinase CK2 has emerged as an attractive therapeutic target in acute myeloid leukemia (AML), an advent that becomes particularly relevant since the treatment of this hematological neoplasia remains challenging. Here we explored for the first time the effect of the clinical-grade peptide-based...

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Gepubliceerd in:Biomedicines
Hoofdauteurs: Rosales, Mauro, Pérez, George V., Ramón, Ailyn C., Cruz, Yiliam, Rodríguez-Ulloa, Arielis, Besada, Vladimir, Ramos, Yassel, Vázquez-Blomquist, Dania, Caballero, Evelin, Aguilar, Daylen, González, Luis J., Zettl, Katharina, Wiśniewski, Jacek R., Yang, Ke, Perera, Yasser, Perea, Silvio E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301452/
https://ncbi.nlm.nih.gov/pubmed/34356831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9070766
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