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Glutamine Synthetase as a Therapeutic Target for Cancer Treatment

The significance of glutamine in cancer metabolism has been extensively studied. Cancer cells consume an excessive amount of glutamine to facilitate rapid proliferation. Thus, glutamine depletion occurs in various cancer types, especially in poorly vascularized cancers. This makes glutamine syntheta...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kim, Go Woon, Lee, Dong Hoon, Jeon, Yu Hyun, Yoo, Jung, Kim, So Yeon, Lee, Sang Wu, Cho, Ha Young, Kwon, So Hee
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915753/
https://ncbi.nlm.nih.gov/pubmed/33567690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041701
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