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HDAC6-Selective Inhibitor Overcomes Bortezomib Resistance in Multiple Myeloma

Although multiple myeloma (MM) patients benefit from standard bortezomib (BTZ) chemotherapy, they develop drug resistance, resulting in relapse. We investigated whether histone deacetylase 6 (HDAC6) inhibitor A452 overcomes bortezomib resistance in MM. We show that HDAC6-selective inhibitor A452 sig...

詳細記述

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書誌詳細
出版年:Int J Mol Sci
主要な著者: Lee, Sang Wu, Yeon, Soo-Keun, Kim, Go Woon, Lee, Dong Hoon, Jeon, Yu Hyun, Yoo, Jung, Kim, So Yeon, Kwon, So Hee
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7866276/
https://ncbi.nlm.nih.gov/pubmed/33572814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22031341
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