Nuclear Receptor Nur77 Controls Cardiac Fibrosis through Distinct Actions on Fibroblasts and Cardiomyocytes

Fibrosis is a hallmark of adverse cardiac remodeling, which promotes heart failure, but it is also an essential repair mechanism to prevent cardiac rupture, signifying the importance of appropriate regulation of this process. In the remodeling heart, cardiac fibroblasts (CFs) differentiate into myof...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Medzikovic, Lejla, Heese, Hylja, van Loenen, Pieter B., van Roomen, Cindy P. A. A., Hooijkaas, Ingeborg B., Christoffels, Vincent M., Creemers, Esther E., de Vries, Carlie J. M., de Waard, Vivian
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915046/
https://ncbi.nlm.nih.gov/pubmed/33562500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22041600
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