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Alignment free identification of clones in B cell receptor repertoires

Following antigenic challenge, activated B cells rapidly expand and undergo somatic hypermutation, yielding groups of clonally related B cells with diversified immunoglobulin receptors. Inference of clonal relationships based on the receptor sequence is an essential step in many adaptive immune rece...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Lindenbaum, Ofir, Nouri, Nima, Kluger, Yuval, Kleinstein, Steven H
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7913774/
https://ncbi.nlm.nih.gov/pubmed/33330933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1160
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