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A spectral clustering-based method for identifying clones from high-throughput B cell repertoire sequencing data

MOTIVATION: B cells derive their antigen-specificity through the expression of Immunoglobulin (Ig) receptors on their surface. These receptors are initially generated stochastically by somatic re-arrangement of the DNA and further diversified following antigen-activation by a process of somatic hype...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bioinformatics
Prif Awduron: Nouri, Nima, Kleinstein, Steven H
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022594/
https://ncbi.nlm.nih.gov/pubmed/29949968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty235
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