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Somatic hypermutation analysis for improved identification of B cell clonal families from next-generation sequencing data
Adaptive immune receptor repertoire sequencing (AIRR-Seq) offers the possibility of identifying and tracking B cell clonal expansions during adaptive immune responses. Members of a B cell clone are descended from a common ancestor and share the same initial V(D)J rearrangement, but their B cell rece...
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| Udgivet i: | PLoS Comput Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7347241/ https://ncbi.nlm.nih.gov/pubmed/32574157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007977 |
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